Modulation of proton ATPase activity in MDCK ‐ C11 cells
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چکیده
منابع مشابه
Cl- and regulation of pH by MDCK-C11 cells.
The interaction between H(+) extrusion via H(+)-ATPase and Cl(-) conductance was studied in the C11 clone of MDCK cells, akin to the intercalated cells of the collecting duct. Cell pH (pHi) was measured by fluorescence microscopy using the fluorescein-derived probe BCECF-AM. Control recovery rate measured after a 20 mM NH(4)Cl acid pulse was 0.136 +/- 0.008 pH units/min (dpHi/dt) in Na(+) Ringe...
متن کاملShear stress-induced volume decrease in C11-MDCK cells by BK- / 4
Holtzclaw JD, Liu L, Grimm PR, Sansom SC. Shear stressinduced volume decrease in C11-MDCK cells by BK/ 4. Am J Physiol Renal Physiol 299: F507–F516, 2010. First published June 24, 2010; doi:10.1152/ajprenal.00222.2010.—Large-conductance, calcium-activated potassium channels (BK) are expressed in principal cells (PC) and intercalated cells (IC) in mammalian nephrons as BK/ 1 and BK/ 4, respectiv...
متن کاملPurinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter.
Purinergic inhibition of Na-K-Cl cotransport has been noted in various renal epithelial cells derived from the collecting tubule, including Madin-Darby canine kidney (MDCK) cells. In recent studies, we have observed purinergic inhibition of Na-K-Cl cotransport in C11-MDCK subclones (alpha-intercalated-like cells). Interestingly, Na-K-Cl cotransport activity was also detected in C7-MDCK subclone...
متن کاملActivation of P2Y receptors causes strong and persistent shrinkage of C11-MDCK renal epithelial cells.
Purinergic receptors activate diverse signaling cascades and regulate the activity of cell volume-sensitive ion transporters. However, the effects of ATP and other agonists of P2 receptors on cell volume dynamics are only scarcely studied. In the present work, we used the recently developed dual-image surface reconstruction technique to explore the influence of purinergic agonists on cell volum...
متن کاملcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.760.4